It is so easy to jump to conclusions when observing and studying honeybees. To the uninitiated, the female workers seem to be the key to the hive. After all, they do so much. They start off early in their lives cleaning the nest. A few days later they are feeding larvae, then secreting wax to build the honeycomb. At about the age of 20 days, they act as guards to the entrance of the nest, and when their glands degenerate, they’re off collecting pollen and nectar for the rest of their lives. After a successful trip, they perform elaborate symbolic dances, revealing both the angular and scalar components of their displacement from flowers to hive. In contrast, the males and the queen bee don’t do any of the above.

But the female workers, as industrious as they may be, do not reproduce and do not exert the strongest influence in the hive. The failure of a single and other type of individual is consistently listed as a cause of honeybee colony mortality.  That individual is the queen bee. She is born in a cell built larger than the others to accommodate her bigger size. But what makes her develop into a queen? After observing that the queen bee larva and adult queen is only fed a so-called royal jelly, a white mixture of protein and sugar secreted from the heads of worker bees, it was long assumed that the mixture held the secret. But a few years ago it was revealed that the key was not necessarily contained in the royal jelly but in what the queen bee was not fed: pollen and nectar. The latter food- source for other larvae contains flavonoids, some of which include inhibitors. Investigators reared larvae in the lab on a royal jelly diet adulterated with para coumaric acid, and by the time they developed into adults, ovary development had been stunted.

Read the full article here: Queen Bee Chemistry — Sciences In the Mural Of Life